Induction of Pro-Apoptotic Endoplasmic Reticulum Stress in Multiple Myeloma Cells by NEO214, Perillyl Alcohol Conjugated to Rolipram

Despite the introduction of new therapies for multiple myeloma (MM), many patients are still dying from this disease and novel treatments are urgently needed. We have designed a novel hybrid molecule, called NEO214, that was generated by covalent conjugation of the natural monoterpene perillyl alcoh...

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Detalles Bibliográficos
Autores principales: Chen, Thomas C., Chan, Nymph, Labib, Shirin, Yu, Jiali, Cho, Hee-Yeon, Hofman, Florence M., Schönthal, Axel H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796223/
https://www.ncbi.nlm.nih.gov/pubmed/29342125
http://dx.doi.org/10.3390/ijms19010277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796223/
https://www.ncbi.nlm.nih.gov/pubmed/29342125
http://dx.doi.org/10.3390/ijms19010277

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