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Induction of Pro-Apoptotic Endoplasmic Reticulum Stress in Multiple Myeloma Cells by NEO214, Perillyl Alcohol Conjugated to Rolipram
Despite the introduction of new therapies for multiple myeloma (MM), many patients are still dying from this disease and novel treatments are urgently needed. We have designed a novel hybrid molecule, called NEO214, that was generated by covalent conjugation of the natural monoterpene perillyl alcoh...
Autores principales: | Chen, Thomas C., Chan, Nymph, Labib, Shirin, Yu, Jiali, Cho, Hee-Yeon, Hofman, Florence M., Schönthal, Axel H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796223/ https://www.ncbi.nlm.nih.gov/pubmed/29342125 http://dx.doi.org/10.3390/ijms19010277 |
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