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Parthenolide facilitates apoptosis and reverses drug-resistance of human gastric carcinoma cells by inhibiting the STAT3 signaling pathway

In the present study, SGC-7901/DDP cells were treated with different concentrations of parthenolide (PN) (2.5–15 µmol/l), cisplatin (DDP) (1.25–15 µg/ml) and PN+DDP. The proliferation inhibition rates were measured using an MTT assay, and the synergies of PN and DDP were analyzed. The effect of PN a...

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Detalles Bibliográficos
Autores principales: Li, Hua, Lu, Hang, Lv, Meng, Wang, Qingsheng, Sun, Yuping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796286/
https://www.ncbi.nlm.nih.gov/pubmed/29467878
http://dx.doi.org/10.3892/ol.2018.7739