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Precise preoperative diagnosis of struma ovarii with pseudo-Meigs’ syndrome mimicking ovarian cancer with the combination of (131)I scintigraphy and (18)F–FDG PET: case report and review of the literature

BACKGROUND: Struma ovarii is a rare ovarian neoplasm that often appears malignant on conventional imaging. Pseudo-Meigs’ syndrome with ascites, pleural effusion, and elevated serum CA 125 levels is much rarer and leads to misdiagnosis of ovarian cancer and unnecessary extended surgery. CASE PRESENTA...

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Autores principales: Fujiwara, Sayaka, Tsuyoshi, Hideaki, Nishimura, Toshiya, Takahashi, Nozomu, Yoshida, Yoshio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796437/
https://www.ncbi.nlm.nih.gov/pubmed/29391043
http://dx.doi.org/10.1186/s13048-018-0383-2
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author Fujiwara, Sayaka
Tsuyoshi, Hideaki
Nishimura, Toshiya
Takahashi, Nozomu
Yoshida, Yoshio
author_facet Fujiwara, Sayaka
Tsuyoshi, Hideaki
Nishimura, Toshiya
Takahashi, Nozomu
Yoshida, Yoshio
author_sort Fujiwara, Sayaka
collection PubMed
description BACKGROUND: Struma ovarii is a rare ovarian neoplasm that often appears malignant on conventional imaging. Pseudo-Meigs’ syndrome with ascites, pleural effusion, and elevated serum CA 125 levels is much rarer and leads to misdiagnosis of ovarian cancer and unnecessary extended surgery. CASE PRESENTATION: A 50-year-old woman with abdominal distention and dyspnoea was referred to our hospital. Ultrasound, computed tomography (CT), and magnetic resonance imaging (MRI) showed a polycystic ovarian tumor with a solid component, pleural effusion, and massive ascites with negative cytology. Her serum CA 125 level was 1237 U/ml, indicating the presence of ovarian cancer. Based on increased uptake of (131)I but no uptake of (18)F–FDG in the tumor, the preoperative diagnosis was struma ovarii with pseudo-Meigs’ syndrome, which was confirmed histologically. She had no evidence of ascites and pleural effusion six months after surgery. CONCLUSIONS: To date, there have been no systematic reviews focused on preoperative diagnosis with imaging modalities. The combination of (131)I scintigraphy and (18)F–FDG PET/CT in addition to conventional imaging modalities can provide the precise preoperative diagnosis of struma ovarii with pseudo-Meigs’ syndrome mimicking ovarian cancer, leading to the appropriate treatment strategy.
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spelling pubmed-57964372018-02-12 Precise preoperative diagnosis of struma ovarii with pseudo-Meigs’ syndrome mimicking ovarian cancer with the combination of (131)I scintigraphy and (18)F–FDG PET: case report and review of the literature Fujiwara, Sayaka Tsuyoshi, Hideaki Nishimura, Toshiya Takahashi, Nozomu Yoshida, Yoshio J Ovarian Res Case Report BACKGROUND: Struma ovarii is a rare ovarian neoplasm that often appears malignant on conventional imaging. Pseudo-Meigs’ syndrome with ascites, pleural effusion, and elevated serum CA 125 levels is much rarer and leads to misdiagnosis of ovarian cancer and unnecessary extended surgery. CASE PRESENTATION: A 50-year-old woman with abdominal distention and dyspnoea was referred to our hospital. Ultrasound, computed tomography (CT), and magnetic resonance imaging (MRI) showed a polycystic ovarian tumor with a solid component, pleural effusion, and massive ascites with negative cytology. Her serum CA 125 level was 1237 U/ml, indicating the presence of ovarian cancer. Based on increased uptake of (131)I but no uptake of (18)F–FDG in the tumor, the preoperative diagnosis was struma ovarii with pseudo-Meigs’ syndrome, which was confirmed histologically. She had no evidence of ascites and pleural effusion six months after surgery. CONCLUSIONS: To date, there have been no systematic reviews focused on preoperative diagnosis with imaging modalities. The combination of (131)I scintigraphy and (18)F–FDG PET/CT in addition to conventional imaging modalities can provide the precise preoperative diagnosis of struma ovarii with pseudo-Meigs’ syndrome mimicking ovarian cancer, leading to the appropriate treatment strategy. BioMed Central 2018-02-02 /pmc/articles/PMC5796437/ /pubmed/29391043 http://dx.doi.org/10.1186/s13048-018-0383-2 Text en © The Author(s). 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Fujiwara, Sayaka
Tsuyoshi, Hideaki
Nishimura, Toshiya
Takahashi, Nozomu
Yoshida, Yoshio
Precise preoperative diagnosis of struma ovarii with pseudo-Meigs’ syndrome mimicking ovarian cancer with the combination of (131)I scintigraphy and (18)F–FDG PET: case report and review of the literature
title Precise preoperative diagnosis of struma ovarii with pseudo-Meigs’ syndrome mimicking ovarian cancer with the combination of (131)I scintigraphy and (18)F–FDG PET: case report and review of the literature
title_full Precise preoperative diagnosis of struma ovarii with pseudo-Meigs’ syndrome mimicking ovarian cancer with the combination of (131)I scintigraphy and (18)F–FDG PET: case report and review of the literature
title_fullStr Precise preoperative diagnosis of struma ovarii with pseudo-Meigs’ syndrome mimicking ovarian cancer with the combination of (131)I scintigraphy and (18)F–FDG PET: case report and review of the literature
title_full_unstemmed Precise preoperative diagnosis of struma ovarii with pseudo-Meigs’ syndrome mimicking ovarian cancer with the combination of (131)I scintigraphy and (18)F–FDG PET: case report and review of the literature
title_short Precise preoperative diagnosis of struma ovarii with pseudo-Meigs’ syndrome mimicking ovarian cancer with the combination of (131)I scintigraphy and (18)F–FDG PET: case report and review of the literature
title_sort precise preoperative diagnosis of struma ovarii with pseudo-meigs’ syndrome mimicking ovarian cancer with the combination of (131)i scintigraphy and (18)f–fdg pet: case report and review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796437/
https://www.ncbi.nlm.nih.gov/pubmed/29391043
http://dx.doi.org/10.1186/s13048-018-0383-2
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