Cargando…

Short-course antimicrobial therapy for paediatric respiratory infections (SAFER): study protocol for a randomized controlled trial

BACKGROUND: Community-acquired pneumonia (CAP) is commonly diagnosed in children. The Infectious Disease Society of America guidelines recommend 10 days of high-dose amoxicillin for the treatment of non-severe CAP but 5-day “short course” therapy may be just as effective. Randomized trials in adults...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pernica, Jeffrey, Harman, Stuart, Kam, April, Bailey, Jacob, Carciumaru, Redjana, Khan, Sarah, Fulford, Martha, Thabane, Lehana, Slinger, Robert, Main, Cheryl, Smieja, Marek, Loeb, Mark
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Study Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796490/ https://www.ncbi.nlm.nih.gov/pubmed/29391051 http://dx.doi.org/10.1186/s13063-018-2457-2

Ejemplares similares

171. Short-course Antimicrobial Therapy for Paediatric Respiratory Infections (SAFER): a multicentre, Randomized, Controlled, Blinded, Noninferiority Trial
por: Pernica, Jeffrey, et al.
Publicado: (2020)

1363. Assessment and Quantification of Nasopharyngeal Streptococcus pneumoniae Colonization Does Not Discriminate Between Children with Viral and Bacterial Respiratory Infection
por: Pernica, Jeffrey, et al.
Publicado: (2020)

Assessment of nasopharyngeal Streptococcus pneumoniae colonization does not permit discrimination between Canadian children with viral and bacterial respiratory infection: a matched-cohort cross-sectional study
por: Pernica, Jeffrey M., et al.
Publicado: (2021)

Novel care pathway to optimise antimicrobial prescribing for uncomplicated community-acquired pneumonia: study protocol for a prospective before–after cohort study in the emergency department of a tertiary care Canadian children’s hospital
por: Pernica, Jeffrey M, et al.
Publicado: (2022)

Single-centre, open-label, randomised, trial to compare rapid molecular point-of-care streptococcal testing to standard laboratory-based testing for the management of streptococcal pharyngitis in children: study protocol
por: Pernica, Jeffrey M, et al.
Publicado: (2021)

Intravenous ketorolac versus morphine in children presenting with suspected appendicitis: a pilot single-centre non-inferiority randomised controlled trial
por: Eltorki, Mohamed, et al.
Publicado: (2022)

Paediatric critical illness associated with respiratory infection: a single-centre, retrospective cohort study
por: Alfaraidi, Haifa, et al.
Publicado: (2020)

Rapid enteric testing to permit targeted antimicrobial therapy, with and without Lactobacillus reuteri probiotics, for paediatric acute diarrhoeal disease in Botswana: A pilot, randomized, factorial, controlled trial
por: Pernica, Jeffrey M., et al.
Publicado: (2017)

Correction: Rapid enteric testing to permit targeted antimicrobial therapy, with and without Lactobacillus reuteri probiotics, for paediatric acute diarrhoeal disease in Botswana: A pilot, randomized, factorial, controlled trial
por: Pernica, Jeffrey M., et al.
Publicado: (2018)

Can an antimicrobial stewardship program reduce length of stay of immune-competent adult patients admitted to hospital with diagnosis of community-acquired pneumonia? Study protocol for pragmatic controlled non-randomized clinical study
por: DiDiodato, Giulio, et al.
Publicado: (2015)

Mobile phone text messaging interventions for HIV and other chronic diseases: an overview of systematic reviews and framework for evidence transfer
por: Mbuagbaw, Lawrence, et al.
Publicado: (2015)

Effect of smoking on lung function, respiratory symptoms and respiratory diseases amongst HIV-positive subjects: a cross-sectional study
por: Cui, Qu, et al.
Publicado: (2010)

Trends and determining factors associated with adherence to antiretroviral therapy (ART) in Cameroon: a systematic review and analysis of the CAMPS trial
por: Mbuagbaw, Lawrence, et al.
Publicado: (2012)

A framework for community ownership of a text messaging programme to improve adherence to antiretroviral therapy and client-provider communication: a mixed methods study
por: Mbuagbaw, Lawrence, et al.
Publicado: (2014)

Severe late-onset multisystem cytomegalovirus infection in a premature neonate previously treated for congenital infection
por: El-Sayed, Manal F, et al.
Publicado: (2013)

GloveCare: a pilot study in preparation for a cluster crossover randomized controlled trial of non-sterile glove-based care in preventing late-onset infection in the NICU
por: Khan, Sarah, et al.
Publicado: (2023)

Real-time polymerase chain reaction for microbiological diagnosis of parapneumonic effusions in Canadian children
por: Pernica, Jeffrey M, et al.
Publicado: (2014)

The Cameroon Mobile Phone SMS (CAMPS) Trial: A Randomized Trial of Text Messaging versus Usual Care for Adherence to Antiretroviral Therapy
por: Mbuagbaw, Lawrence, et al.
Publicado: (2012)

Rapid paediatric fluid resuscitation: a randomised controlled trial comparing the efficiency of two provider-endorsed manual paediatric fluid resuscitation techniques in a simulated setting
por: Cole, Evan T, et al.
Publicado: (2014)

Antibiotic therapy for skin and soft tissue infections: a protocol for a systematic review and network meta-analysis
por: Bartoszko, Jessica J., et al.
Publicado: (2018)

Direct Streptococcus pneumoniae real-time PCR serotyping from pediatric parapneumonic effusions
por: Slinger, Robert, et al.
Publicado: (2014)

Oseltamivir use amongst hospitalized patients infected with influenza
por: Herman, Michael, et al.
Publicado: (2014)

Study protocol for a randomised controlled trial comparing the efficiency of two provider-endorsed manual paediatric fluid resuscitation techniques
por: Cole, Evan T, et al.
Publicado: (2013)

A predictive model to differentiate dengue from other febrile illness
por: Fernández, Eduardo, et al.
Publicado: (2016)

A retrospective cohort study to predict severe dengue in Honduran patients
por: Fernández, Eduardo, et al.
Publicado: (2017)

Comparison of brachial and carotid artery ultrasound for assessing extent of subclinical atherosclerosis in HIV: a prospective cohort study
por: Odueyungbo, Adefowope, et al.
Publicado: (2009)

WHO Safer Surgery checklist compliance amongst paediatric emergency plastic surgery patients in an UK hospital
por: Keijzer, Welmoed W., et al.
Publicado: (2017)

Pandemic (H1N1) 2009 Risk for Nurses after Trivalent Vaccination
por: Loeb, Mark, et al.
Publicado: (2010)

Pharmacotherapy in paediatric type 2 diabetes mellitus: a protocol for a systematic review and network meta-analysis of randomised trials
por: Zhou, Fangwen, et al.
Publicado: (2022)

Mobile phone text messages for improving adherence to antiretroviral therapy (ART): a protocol for an individual patient data meta-analysis of randomised trials
por: Mbuagbaw, Lawrence, et al.
Publicado: (2013)

Children hospitalized with community-acquired pneumonia complicated by effusion: a single-centre retrospective cohort study
por: Alemayheu, Gelila, et al.
Publicado: (2023)

SAFER CANCER CHEMOTHERAPY
Publicado: (1981)

Safer drugs for children.
Publicado: (1999)

Safer Hospital Care
por: Raheja, Dev
Publicado: (2016)

Designing Safer Chemicals
por: Birnbaum, Linda S.
Publicado: (2013)

Safer ocular anaesthesia
por: Eke, Tom
Publicado: (2016)

To Make the Water Safer
por: Li, Peiyue
Publicado: (2020)

Safer Roads to School
por: Agrawal, Amit, et al.
Publicado: (2020)

Mobile phone text messages for improving adherence to antiretroviral therapy (ART): an individual patient data meta-analysis of randomised trials
por: Mbuagbaw, Lawrence, et al.
Publicado: (2013)

Tips for charting the course of a successful health research career
por: Mbuagbaw, Lawrence, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_pnielni1vva2tbf294mlme9jp9