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New insight into transglutaminase 2 and link to neurodegenerative diseases

Formation of toxic protein aggregates is a common feature and mainly contributes to the pathogenesis of neurodegenerative diseases (NDDs), which include amyotrophic lateral sclerosis (ALS), Alzheimer’s, Parkinson’s, Huntington’s, and prion diseases. The transglutaminase 2 (TG2) gene encodes a multif...

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Detalles Bibliográficos
Autores principales: Min, Boram, Chung, Kwang Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796628/
https://www.ncbi.nlm.nih.gov/pubmed/29187283
http://dx.doi.org/10.5483/BMBRep.2018.51.1.227