The natural anti-tumor compound Celastrol targets a Myb-C/EBPβ-p300 transcriptional module implicated in myeloid gene expression

Myb is a key regulator of hematopoietic progenitor cell proliferation and differentiation and has emerged as a potential target for the treatment of acute leukemia. Using a myeloid cell line with a stably integrated Myb-inducible reporter gene as a screening tool we have previously identified Celast...

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Detalles Bibliográficos
Autores principales: Coulibaly, Anna, Haas, Astrid, Steinmann, Simone, Jakobs, Anke, Schmidt, Thomas J., Klempnauer, Karl-Heinz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796697/
https://www.ncbi.nlm.nih.gov/pubmed/29394256
http://dx.doi.org/10.1371/journal.pone.0190934

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796697/
https://www.ncbi.nlm.nih.gov/pubmed/29394256
http://dx.doi.org/10.1371/journal.pone.0190934

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