An Mll4/COMPASS-Lsd1 epigenetic axis governs enhancer function and pluripotency transition in embryonic stem cells

Chromatin regulators control cellular differentiation by orchestrating dynamic developmental gene expression programs, and hence, malfunctions in the regulation of chromatin state contribute to both developmental disorders and disease state. Mll4 (Kmt2d), a member of the COMPASS (COMplex of Proteins...

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Detalles Bibliográficos
Autores principales: Cao, Kaixiang, Collings, Clayton K., Morgan, Marc A., Marshall, Stacy A., Rendleman, Emily J., Ozark, Patrick A., Smith, Edwin R., Shilatifard, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796793/
https://www.ncbi.nlm.nih.gov/pubmed/29404406
http://dx.doi.org/10.1126/sciadv.aap8747

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796793/
https://www.ncbi.nlm.nih.gov/pubmed/29404406
http://dx.doi.org/10.1126/sciadv.aap8747

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