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Core Fucosylation of the T Cell Receptor Is Required for T Cell Activation

CD4(+) T cell activation promotes the pathogenic process of systemic lupus erythematosus (SLE). T cell receptor (TCR) complex are highly core fucosylated glycoproteins, which play important roles in T cell activation. In this study, we found that the core fucosylation of CD4(+) T cells was significa...

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Detalles Bibliográficos
Autores principales: Liang, Wei, Mao, Shanshan, Sun, Shijie, Li, Ming, Li, Zhi, Yu, Rui, Ma, Tonghui, Gu, Jianguo, Zhang, Jianing, Taniguchi, Naoyuki, Li, Wenzhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796888/
https://www.ncbi.nlm.nih.gov/pubmed/29434598
http://dx.doi.org/10.3389/fimmu.2018.00078