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The Activin A-Peroxisome Proliferator-Activated Receptor Gamma Axis Contributes to the Transcriptome of GM-CSF-Conditioned Human Macrophages

GM-CSF promotes the functional maturation of lung alveolar macrophages (A-MØ), whose differentiation is dependent on the peroxisome proliferator-activated receptor gamma (PPARγ) transcription factor. In fact, blockade of GM-CSF-initiated signaling or deletion of the PPARγ-encoding gene PPARG leads t...

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Detalles Bibliográficos
Autores principales:	Nieto, Concha, Bragado, Rafael, Municio, Cristina, Sierra-Filardi, Elena, Alonso, Bárbara, Escribese, María M., Domínguez-Andrés, Jorge, Ardavín, Carlos, Castrillo, Antonio, Vega, Miguel A., Puig-Kröger, Amaya, Corbí, Angel L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796898/ https://www.ncbi.nlm.nih.gov/pubmed/29434585 http://dx.doi.org/10.3389/fimmu.2018.00031

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