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Identification of a Novel CD8 T Cell Epitope Derived from Plasmodium berghei Protective Liver-Stage Antigen

We recently identified novel Plasmodium berghei (Pb) liver stage (LS) genes that as DNA vaccines significantly reduce Pb LS parasite burden (LPB) in C57Bl/6 (B6) mice through a mechanism mediated, in part, by CD8 T cells. In this study, we sought to determine fine antigen (Ag) specificities of CD8 T...

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Detalles Bibliográficos
Autores principales:	Pichugin, Alexander, Zarling, Stasya, Perazzo, Leah, Duffy, Patrick Emmet, Ploegh, Hidde Lolke, Krzych, Urszula
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796907/ https://www.ncbi.nlm.nih.gov/pubmed/29434602 http://dx.doi.org/10.3389/fimmu.2018.00091

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