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Cilostazol induced migraine does not respond to sumatriptan in a double blind trial

BACKGROUND: Cilostazol is an inhibitor of phosphodiesterase 3 and thus causes accumulation of cAMP. It induces migraine-like attacks in migraine patients. Whether the cilostazol model responds to sumatriptan in migraine patients and therefore is valid for testing of future anti-migraine medications...

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Detalles Bibliográficos
Autores principales: Falkenberg, Katrine, Dunga, Bára Óladóttir á, Guo, Song, Ashina, Messoud, Olesen, Jes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Milan 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796931/
https://www.ncbi.nlm.nih.gov/pubmed/29396788
http://dx.doi.org/10.1186/s10194-018-0841-7