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Clinical and molecular features of innate and acquired resistance to anti-PD-1/PD-L1 therapy in lung cancer
HYPOTHESIS: The majority of non-small cell lung cancer (NSCLC) patients treated with anti-PD-1/PD-L1 therapy develop either innate or acquired resistance. Across tumor types, the “T cell-inflamed” tumor microenvironment correlates with clinical response to immunotherapy. We hypothesize that clinical...
Autores principales: | Shah, Shalin, Wood, Kevin, Labadie, Brian, Won, Brian, Brisson, Ryan, Karrison, Theodore, Hensing, Thomas, Kozloff, Mark, Bao, Riyue, Patel, Jyoti D., Luke, Jason J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796980/ https://www.ncbi.nlm.nih.gov/pubmed/29435109 http://dx.doi.org/10.18632/oncotarget.23315 |
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