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Induction of endoplasmic reticulum stress and mitochondrial dysfunction dependent apoptosis signaling pathway in human renal cancer cells by norcantharidin

Previous studies reported that norcantharidin (NCTD) has anti-tumor effects. We investigated the antitumor effects and underlying mechanism of NCTD on human renal cancer in vitro and in vivo. NCTD significantly decreased renal cancer cell viability by induction of apoptosis, as determined by the MTT...

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Detalles Bibliográficos
Autores principales: Wu, Min-Hua, Chiou, Hui-Ling, Lin, Chu-Liang, Lin, Ching-Yi, Yang, Shun-Fa, Hsieh, Yi-Hsien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797012/
https://www.ncbi.nlm.nih.gov/pubmed/29435141
http://dx.doi.org/10.18632/oncotarget.23465