Nonlinear mixed effects dose response modeling in high throughput drug screens: application to melanoma cell line analysis

Cancer cell lines are often used in high throughput drug screens (HTS) to explore the relationship between cell line characteristics and responsiveness to different therapies. Many current analysis methods infer relationships by focusing on one aspect of cell line drug-specific dose-response curves...

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Detalles Bibliográficos
Autores principales: Ding, Kuan-Fu, Petricoin, Emanuel F., Finlay, Darren, Yin, Hongwei, Hendricks, William P.D., Sereduk, Chris, Kiefer, Jeffrey, Sekulic, Aleksandar, LoRusso, Patricia M., Vuori, Kristiina, Trent, Jeffrey M., Schork, Nicholas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797032/
https://www.ncbi.nlm.nih.gov/pubmed/29435161
http://dx.doi.org/10.18632/oncotarget.23495

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