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REST upregulates gremlin to modulate diffuse intrinsic pontine glioma vasculature

Diffuse intrinsic pontine glioma (DIPG) is a highly aggressive glial tumor that occurs in children. The extremely poor median and 5-year survival in children afflicted with DIPG highlights the need for novel biology-driven therapeutics. Here, we have implicated the chromatin remodeler and regulator...

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Detalles Bibliográficos
Autores principales: Shaik, Shavali, Kennis, Bridget, Maegawa, Shinji, Schadler, Keri, Yanwen, Yang, Callegari, Keri, Lulla, Rishi R., Goldman, Stewart, Nazarian, Javad, Rajaram, Veena, Fangusaro, Jason, Gopalakrishnan, Vidya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797046/
https://www.ncbi.nlm.nih.gov/pubmed/29435175
http://dx.doi.org/10.18632/oncotarget.23750