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Exon 3 mutations of CTNNB1 drive tumorigenesis: a review

The canonical Wnt/β-catenin signaling pathway, an important modulator of progenitor cell proliferation and differentiation, is highly regulated for the maintenance of critical biological homeostasis. Decades of studies in cancer genetics and genomics have demonstrated that multiple genes encoding ke...

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Detalles Bibliográficos
Autores principales: Gao, Chao, Wang, Yingmei, Broaddus, Russell, Sun, Longhao, Xue, Fengxia, Zhang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797067/
https://www.ncbi.nlm.nih.gov/pubmed/29435196
http://dx.doi.org/10.18632/oncotarget.23695

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