Demonstration of ion channel synthesis by isolated squid giant axon provides functional evidence for localized axonal membrane protein translation

Local translation of membrane proteins in neuronal subcellular domains like soma, dendrites and axon termini is well-documented. In this study, we isolated the electrical signaling unit of an axon by dissecting giant axons from mature squids (Dosidicus gigas). Axoplasm extracted from these axons was...

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Detalles Bibliográficos
Autores principales: Mathur, Chhavi, Johnson, Kory R., Tong, Brian A., Miranda, Pablo, Srikumar, Deepa, Basilio, Daniel, Latorre, Ramon, Bezanilla, Francisco, Holmgren, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797086/
https://www.ncbi.nlm.nih.gov/pubmed/29396520
http://dx.doi.org/10.1038/s41598-018-20684-8

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