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The anillin-related Int1 protein and the Sep7 septin collaborate to maintain cellular ploidy in Candida albicans
Variation in cell ploidy is a common feature of Candida albicans clinical isolates that are resistant to the antifungal drug fluconazole. Here, we report that the anillin-related protein Int1 interacts with septins for coupling cytokinesis with nuclear segregation. Loss of Int1 results in a rapid di...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797091/ https://www.ncbi.nlm.nih.gov/pubmed/29396461 http://dx.doi.org/10.1038/s41598-018-20249-9 |