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PCSK9 induces a pro-inflammatory response in macrophages
Intraplaque release of inflammatory cytokines from macrophages is implicated in atherogenesis by inducing the proliferation and migration of media smooth muscle cells (SMCs). PCSK9 is present and released by SMCs within the atherosclerotic plaque but its function is still unknown. In the present stu...
Autores principales: | Ricci, Chiara, Ruscica, Massimiliano, Camera, Marina, Rossetti, Laura, Macchi, Chiara, Colciago, Alessandra, Zanotti, Ilaria, Lupo, Maria Giovanna, Adorni, Maria Pia, Cicero, Arrigo F. G., Fogacci, Federica, Corsini, Alberto, Ferri, Nicola |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797178/ https://www.ncbi.nlm.nih.gov/pubmed/29396513 http://dx.doi.org/10.1038/s41598-018-20425-x |
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