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PCSK9 induces a pro-inflammatory response in macrophages

Intraplaque release of inflammatory cytokines from macrophages is implicated in atherogenesis by inducing the proliferation and migration of media smooth muscle cells (SMCs). PCSK9 is present and released by SMCs within the atherosclerotic plaque but its function is still unknown. In the present stu...

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Detalles Bibliográficos
Autores principales: Ricci, Chiara, Ruscica, Massimiliano, Camera, Marina, Rossetti, Laura, Macchi, Chiara, Colciago, Alessandra, Zanotti, Ilaria, Lupo, Maria Giovanna, Adorni, Maria Pia, Cicero, Arrigo F. G., Fogacci, Federica, Corsini, Alberto, Ferri, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797178/
https://www.ncbi.nlm.nih.gov/pubmed/29396513
http://dx.doi.org/10.1038/s41598-018-20425-x

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