Early Detection of Apathetic Phenotypes in Huntington’s Disease Knock-in Mice Using Open Source Tools

Apathy is one of the most prevalent and progressive psychiatric symptoms in Huntington’s disease (HD) patients. However, preclinical work in HD mouse models tends to focus on molecular and motor, rather than affective, phenotypes. Measuring behavior in mice often produces noisy data and requires lar...

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Detalles Bibliográficos
Autores principales: Minnig, Shawn, Bragg, Robert M., Tiwana, Hardeep S., Solem, Wes T., Hovander, William S., Vik, Eva-Mari S., Hamilton, Madeline, Legg, Samuel R. W., Shuttleworth, Dominic D., Coffey, Sydney R., Cantle, Jeffrey P., Carroll, Jeffrey B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797185/
https://www.ncbi.nlm.nih.gov/pubmed/29396492
http://dx.doi.org/10.1038/s41598-018-20607-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797185/
https://www.ncbi.nlm.nih.gov/pubmed/29396492
http://dx.doi.org/10.1038/s41598-018-20607-7

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