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Early Detection of Apathetic Phenotypes in Huntington’s Disease Knock-in Mice Using Open Source Tools
Apathy is one of the most prevalent and progressive psychiatric symptoms in Huntington’s disease (HD) patients. However, preclinical work in HD mouse models tends to focus on molecular and motor, rather than affective, phenotypes. Measuring behavior in mice often produces noisy data and requires lar...
Autores principales: | Minnig, Shawn, Bragg, Robert M., Tiwana, Hardeep S., Solem, Wes T., Hovander, William S., Vik, Eva-Mari S., Hamilton, Madeline, Legg, Samuel R. W., Shuttleworth, Dominic D., Coffey, Sydney R., Cantle, Jeffrey P., Carroll, Jeffrey B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797185/ https://www.ncbi.nlm.nih.gov/pubmed/29396492 http://dx.doi.org/10.1038/s41598-018-20607-7 |
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