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UFD-2 is an adaptor-assisted E3 ligase targeting unfolded proteins

Muscle development requires the coordinated activities of specific protein folding and degradation factors. UFD-2, a U-box ubiquitin ligase, has been reported to play a central role in this orchestra regulating the myosin chaperone UNC-45. Here, we apply an integrative in vitro and in vivo approach...

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Detalles Bibliográficos
Autores principales:	Hellerschmied, Doris, Roessler, Max, Lehner, Anita, Gazda, Linn, Stejskal, Karel, Imre, Richard, Mechtler, Karl, Dammermann, Alexander, Clausen, Tim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797217/ https://www.ncbi.nlm.nih.gov/pubmed/29396393 http://dx.doi.org/10.1038/s41467-018-02924-7

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