Discordant congenital Zika syndrome twins show differential in vitro viral susceptibility of neural progenitor cells

Congenital Zika syndrome (CZS) causes early brain development impairment by affecting neural progenitor cells (NPCs). Here, we analyze NPCs from three pairs of dizygotic twins discordant for CZS. We compare by RNA-Seq the NPCs derived from CZS-affected and CZS-unaffected twins. Prior to Zika virus (...

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Detalles Bibliográficos
Autores principales: Caires-Júnior, Luiz Carlos, Goulart, Ernesto, Melo, Uirá Souto, Araujo, Bruno Henrique Silva, Alvizi, Lucas, Soares-Schanoski, Alessandra, de Oliveira, Danyllo Felipe, Kobayashi, Gerson Shigeru, Griesi-Oliveira, Karina, Musso, Camila Manso, Amaral, Murilo Sena, daSilva, Lucas Ferreira, Astray, Renato Mancini, Suárez-Patiño, Sandra Fernanda, Ventini, Daniella Cristina, Gomes da Silva, Sérgio, Yamamoto, Guilherme Lopes, Ezquina, Suzana, Naslavsky, Michel Satya, Telles-Silva, Kayque Alves, Weinmann, Karina, van der Linden, Vanessa, van der Linden, Helio, de Oliveira, João Ricardo Mendes, Arrais, Nivia Maria Rodrigues, Melo, Adriana, Figueiredo, Thalita, Santos, Silvana, Meira, Joanna Goes Castro, Passos, Saulo Duarte, de Almeida, Roque Pacheco, Bispo, Ana Jovina Barreto, Cavalheiro, Esper Abrão, Kalil, Jorge, Cunha-Neto, Edécio, Nakaya, Helder, Andreata-Santos, Robert, de Souza Ferreira, Luis Carlos, Verjovski-Almeida, Sergio, Ho, Paulo Lee, Passos-Bueno, Maria Rita, Zatz, Mayana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797251/
https://www.ncbi.nlm.nih.gov/pubmed/29396410
http://dx.doi.org/10.1038/s41467-017-02790-9

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