Cargando…
Clinical outcomes of surveillance colonoscopy for patients with sessile serrated adenoma
BACKGROUND/AIMS: Sessile serrated adenomas (SSAs) are known to be precursors of colorectal cancer (CRC). The proper interval of follow-up colonoscopy for SSAs is still being debated. We sought to determine the proper interval of colonoscopy surveillance in patients diagnosed with SSAs in South Korea...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Association for the Study of Intestinal Diseases
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797260/ https://www.ncbi.nlm.nih.gov/pubmed/29422808 http://dx.doi.org/10.5217/ir.2018.16.1.134 |
_version_ | 1783297648237740032 |
---|---|
author | Park, Sung Jae Yoon, Hyuk Jung, In Sub Shin, Cheol Min Park, Young Soo Kim, Na Young Lee, Dong Ho |
author_facet | Park, Sung Jae Yoon, Hyuk Jung, In Sub Shin, Cheol Min Park, Young Soo Kim, Na Young Lee, Dong Ho |
author_sort | Park, Sung Jae |
collection | PubMed |
description | BACKGROUND/AIMS: Sessile serrated adenomas (SSAs) are known to be precursors of colorectal cancer (CRC). The proper interval of follow-up colonoscopy for SSAs is still being debated. We sought to determine the proper interval of colonoscopy surveillance in patients diagnosed with SSAs in South Korea. METHODS: We retrospectively reviewed the medical records of patients diagnosed with SSAs who received 1 or more follow-up colonoscopies. The information reviewed included patient baseline characteristics, SSA characteristics, and colonoscopy information. RESULTS: From January 2007 to December 2011, 152 SSAs and 8 synchronous adenocarcinomas were identified in 138 patients. The mean age of the patients was 62.2 years and 60.1% patients were men. SSAs were located in the right colon (i.e., from the cecum to the hepatic flexure) in 68.4% patients. At the first follow-up, 27 SSAs were identified in 138 patients (right colon, 66.7%). At the second follow-up, 6 SSAs were identified in 65 patients (right colon, 66.7%). At the 3rd and 4th follow-up, 21 and 11 patients underwent colonoscopy, respectively, and no SSAs were detected. The total mean follow-up duration was 33.9 months. The mean size of SSAs was 8.1±5.0 mm. SSAs were most commonly found in the right colon (126/185, 68.1%). During annual follow-up colonoscopy surveillance, no cancer was detected. CONCLUSIONS: Annual colonoscopy surveillance is not necessary for identifying new CRCs in all patients diagnosed with SSAs. In addition, the right colon should be examined more carefully because SSAs occur more frequently in the right colon during initial and follow-up colonoscopies. |
format | Online Article Text |
id | pubmed-5797260 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Korean Association for the Study of Intestinal Diseases |
record_format | MEDLINE/PubMed |
spelling | pubmed-57972602018-02-08 Clinical outcomes of surveillance colonoscopy for patients with sessile serrated adenoma Park, Sung Jae Yoon, Hyuk Jung, In Sub Shin, Cheol Min Park, Young Soo Kim, Na Young Lee, Dong Ho Intest Res Original Article BACKGROUND/AIMS: Sessile serrated adenomas (SSAs) are known to be precursors of colorectal cancer (CRC). The proper interval of follow-up colonoscopy for SSAs is still being debated. We sought to determine the proper interval of colonoscopy surveillance in patients diagnosed with SSAs in South Korea. METHODS: We retrospectively reviewed the medical records of patients diagnosed with SSAs who received 1 or more follow-up colonoscopies. The information reviewed included patient baseline characteristics, SSA characteristics, and colonoscopy information. RESULTS: From January 2007 to December 2011, 152 SSAs and 8 synchronous adenocarcinomas were identified in 138 patients. The mean age of the patients was 62.2 years and 60.1% patients were men. SSAs were located in the right colon (i.e., from the cecum to the hepatic flexure) in 68.4% patients. At the first follow-up, 27 SSAs were identified in 138 patients (right colon, 66.7%). At the second follow-up, 6 SSAs were identified in 65 patients (right colon, 66.7%). At the 3rd and 4th follow-up, 21 and 11 patients underwent colonoscopy, respectively, and no SSAs were detected. The total mean follow-up duration was 33.9 months. The mean size of SSAs was 8.1±5.0 mm. SSAs were most commonly found in the right colon (126/185, 68.1%). During annual follow-up colonoscopy surveillance, no cancer was detected. CONCLUSIONS: Annual colonoscopy surveillance is not necessary for identifying new CRCs in all patients diagnosed with SSAs. In addition, the right colon should be examined more carefully because SSAs occur more frequently in the right colon during initial and follow-up colonoscopies. Korean Association for the Study of Intestinal Diseases 2018-01 2018-01-18 /pmc/articles/PMC5797260/ /pubmed/29422808 http://dx.doi.org/10.5217/ir.2018.16.1.134 Text en © Copyright 2018. Korean Association for the Study of Intestinal Diseases. http://creativecommons.org/licenses/by-nc/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Park, Sung Jae Yoon, Hyuk Jung, In Sub Shin, Cheol Min Park, Young Soo Kim, Na Young Lee, Dong Ho Clinical outcomes of surveillance colonoscopy for patients with sessile serrated adenoma |
title | Clinical outcomes of surveillance colonoscopy for patients with sessile serrated adenoma |
title_full | Clinical outcomes of surveillance colonoscopy for patients with sessile serrated adenoma |
title_fullStr | Clinical outcomes of surveillance colonoscopy for patients with sessile serrated adenoma |
title_full_unstemmed | Clinical outcomes of surveillance colonoscopy for patients with sessile serrated adenoma |
title_short | Clinical outcomes of surveillance colonoscopy for patients with sessile serrated adenoma |
title_sort | clinical outcomes of surveillance colonoscopy for patients with sessile serrated adenoma |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797260/ https://www.ncbi.nlm.nih.gov/pubmed/29422808 http://dx.doi.org/10.5217/ir.2018.16.1.134 |
work_keys_str_mv | AT parksungjae clinicaloutcomesofsurveillancecolonoscopyforpatientswithsessileserratedadenoma AT yoonhyuk clinicaloutcomesofsurveillancecolonoscopyforpatientswithsessileserratedadenoma AT junginsub clinicaloutcomesofsurveillancecolonoscopyforpatientswithsessileserratedadenoma AT shincheolmin clinicaloutcomesofsurveillancecolonoscopyforpatientswithsessileserratedadenoma AT parkyoungsoo clinicaloutcomesofsurveillancecolonoscopyforpatientswithsessileserratedadenoma AT kimnayoung clinicaloutcomesofsurveillancecolonoscopyforpatientswithsessileserratedadenoma AT leedongho clinicaloutcomesofsurveillancecolonoscopyforpatientswithsessileserratedadenoma |