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Angiotensin-(1–7) Promotes Resolution of Eosinophilic Inflammation in an Experimental Model of Asthma

Defective apoptosis of eosinophils, the main leukocyte in the pathogenesis of asthma, and delay in its removal lead to lung damage and loss of pulmonary function due to failure in the resolution of inflammation. Here, we investigated the ability of angiotensin-(1–7) [Ang-(1–7)], a pivotal peptide of...

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Detalles Bibliográficos
Autores principales: Magalhaes, Giselle S., Barroso, Lívia C., Reis, Alesandra C., Rodrigues-Machado, Maria G., Gregório, Juliana F., Motta-Santos, Daisy, Oliveira, Aline C., Perez, Denise A., Barcelos, Lucíola S., Teixeira, Mauro M., Santos, Robson A. S., Pinho, Vanessa, Campagnole-Santos, Maria Jose
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797293/
https://www.ncbi.nlm.nih.gov/pubmed/29434591
http://dx.doi.org/10.3389/fimmu.2018.00058