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Fully-covered metal stents with endoscopic suturing vs. partially-covered metal stents for benign upper gastrointestinal diseases: a comparative study

BACKGROUND AND STUDY AIMS : Self-expandable metallic stents (SEMS) have been increasingly used in benign conditions (e. g. strictures, fistulas, leaks, and perforations). Fully covered SEMS (FSEMS) were introduced to avoid undesirable consequences of partially covered SEMS (PSEMS), but come with hig...

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Detalles Bibliográficos
Autores principales: Ngamruengphong, Saowanee, Sharaiha, Reem, Sethi, Amrita, Siddiqui, Ali, DiMaio, Christopher J., Gonzalez, Susana, Rogart, Jason, Jagroop, Sophia, Widmer, Jessica, Im, Jennifer, Hasan, Raza Abbas, Laique, Sobia, Gonda, Tamas, Poneros, John, Desai, Amit, Wong, Katherine, Villgran, Vipin, Brewer Gutierrez, Olaya, Bukhari, Majidah, Chen, Yen-I, Hernaez, Ruben, Hanada, Yuri, Sanaei, Omid, Agarwal, Amol, Kalloo, Anthony N., Kumbhari, Vivek, Singh, Vikesh, Khashab, Mouen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: © Georg Thieme Verlag KG 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797316/
https://www.ncbi.nlm.nih.gov/pubmed/29404384
http://dx.doi.org/10.1055/s-0043-125363
Descripción
Sumario:BACKGROUND AND STUDY AIMS : Self-expandable metallic stents (SEMS) have been increasingly used in benign conditions (e. g. strictures, fistulas, leaks, and perforations). Fully covered SEMS (FSEMS) were introduced to avoid undesirable consequences of partially covered SEMS (PSEMS), but come with higher risk of stent migration. Endoscopic suturing (ES) for stent fixation has been shown to reduce migration of FSEMS. Our aim was to compare the outcomes of FSEMS with ES (FS/ES) versus PSEMS in patients with benign upper gastrointestinal conditions. PATIENTS AND METHODS : We retrospectively identified all patients who underwent stent placement for benign gastrointestinal conditions at seven US tertiary-care centers. Patients were divided into two groups: FSEMS with ES (FS/ES group) and PSEMS (PSEMS group). Clinical outcomes between the two groups were compared. RESULTS : A total of 74 (FS/ES 46, PSEMS 28) patients were included. On multivariable analysis, there was no significant difference in rate of stent migration between FS/ES (43 %) and PSEMS (15 %) (adjusted odds ratio 0.56; 95 % CI 0.15 – 2.00). Clinical success was similar [68 % vs. 64 %; P  = 0.81]. Rate of adverse events (AEs) was higher in PSEMS group [13 (46 %) vs. 10 (21 %); P  = 0.03). Difficult stent removal was higher in the PSEMS group (n = 5;17 %) vs. 0 % in the FS/ES group; P  = 0.005. CONCLUSIONS : The proportion of stent migration of FS/ES and PSEMS are similar. Rates of other stent-related AEs were higher in the PSEMS group. PSEMS was associated with tissue ingrowth or overgrowth leading to difficult stent removal, and secondary stricture formation. Thus, FSEMS with ES for stent fixation may be the preferred modality over PSEMS for the treatment of benign upper gastrointestinal conditions.