BCN057 induces intestinal stem cell repair and mitigates radiation-induced intestinal injury

BACKGROUND: Radiation-induced gastrointestinal syndrome (RIGS) results from the acute loss of intestinal stem cells (ISC), impaired epithelial regeneration, and subsequent loss of the mucosal barrier, resulting in electrolyte imbalance, diarrhea, weight loss, sepsis, and mortality. The high radiosen...

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Detalles Bibliográficos
Autores principales: Bhanja, Payel, Norris, Andrew, Gupta-Saraf, Pooja, Hoover, Andrew, Saha, Subhrajit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797353/
https://www.ncbi.nlm.nih.gov/pubmed/29394953
http://dx.doi.org/10.1186/s13287-017-0763-3

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