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National Institute for Health Research (NIHR) Health Technology Assessment (HTA) Programme research funding and UK burden of disease

BACKGROUND: HTA Programme funding is governed by the need for evidence and scientific quality, reflecting funding of the National Institute for Health Research (NIHR) by the NHS. The need criterion incorporates covering the spectrum of diseases, but also taking account of research supported by other...

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Autores principales: Chinnery, Fay, Bashevoy, Gemma, Blatch-Jones, Amanda, Douet, Lisa, Puddicombe, Sarah, Raftery, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797405/
https://www.ncbi.nlm.nih.gov/pubmed/29394905
http://dx.doi.org/10.1186/s13063-018-2489-7
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author Chinnery, Fay
Bashevoy, Gemma
Blatch-Jones, Amanda
Douet, Lisa
Puddicombe, Sarah
Raftery, James
author_facet Chinnery, Fay
Bashevoy, Gemma
Blatch-Jones, Amanda
Douet, Lisa
Puddicombe, Sarah
Raftery, James
author_sort Chinnery, Fay
collection PubMed
description BACKGROUND: HTA Programme funding is governed by the need for evidence and scientific quality, reflecting funding of the National Institute for Health Research (NIHR) by the NHS. The need criterion incorporates covering the spectrum of diseases, but also taking account of research supported by other funders. This study compared the NIHR HTA Programme portfolio of research with the UK burden of disease as measured by Disability-adjusted Life Years (DALYs). METHODS: A retrospective cross-sectional study using a cohort of all funded primary research and evidence syntheses projects received by the HTA Programme from April 2011 to March 2016 (n = 363); to determine the proportion of spend by disease compared with burden of disease in the UK calculated using 2015 UK DALY data. RESULTS: The programme costing just under £44 million broadly reflected UK DALY burden by disease. Spend was lower than disease burden for cancer, cardiovascular and musculoskeletal diseases, which may reflect the importance of other funders, notably medical charities, which concentrate on these diseases. CONCLUSION: The HTA Programme spend, adjusted for other relevant funders, broadly matches disease burden in the UK; no diseases are being neglected. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13063-018-2489-7) contains supplementary material, which is available to authorized users.
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spelling pubmed-57974052018-02-12 National Institute for Health Research (NIHR) Health Technology Assessment (HTA) Programme research funding and UK burden of disease Chinnery, Fay Bashevoy, Gemma Blatch-Jones, Amanda Douet, Lisa Puddicombe, Sarah Raftery, James Trials Research BACKGROUND: HTA Programme funding is governed by the need for evidence and scientific quality, reflecting funding of the National Institute for Health Research (NIHR) by the NHS. The need criterion incorporates covering the spectrum of diseases, but also taking account of research supported by other funders. This study compared the NIHR HTA Programme portfolio of research with the UK burden of disease as measured by Disability-adjusted Life Years (DALYs). METHODS: A retrospective cross-sectional study using a cohort of all funded primary research and evidence syntheses projects received by the HTA Programme from April 2011 to March 2016 (n = 363); to determine the proportion of spend by disease compared with burden of disease in the UK calculated using 2015 UK DALY data. RESULTS: The programme costing just under £44 million broadly reflected UK DALY burden by disease. Spend was lower than disease burden for cancer, cardiovascular and musculoskeletal diseases, which may reflect the importance of other funders, notably medical charities, which concentrate on these diseases. CONCLUSION: The HTA Programme spend, adjusted for other relevant funders, broadly matches disease burden in the UK; no diseases are being neglected. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13063-018-2489-7) contains supplementary material, which is available to authorized users. BioMed Central 2018-02-02 /pmc/articles/PMC5797405/ /pubmed/29394905 http://dx.doi.org/10.1186/s13063-018-2489-7 Text en © The Author(s). 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research
Chinnery, Fay
Bashevoy, Gemma
Blatch-Jones, Amanda
Douet, Lisa
Puddicombe, Sarah
Raftery, James
National Institute for Health Research (NIHR) Health Technology Assessment (HTA) Programme research funding and UK burden of disease
title National Institute for Health Research (NIHR) Health Technology Assessment (HTA) Programme research funding and UK burden of disease
title_full National Institute for Health Research (NIHR) Health Technology Assessment (HTA) Programme research funding and UK burden of disease
title_fullStr National Institute for Health Research (NIHR) Health Technology Assessment (HTA) Programme research funding and UK burden of disease
title_full_unstemmed National Institute for Health Research (NIHR) Health Technology Assessment (HTA) Programme research funding and UK burden of disease
title_short National Institute for Health Research (NIHR) Health Technology Assessment (HTA) Programme research funding and UK burden of disease
title_sort national institute for health research (nihr) health technology assessment (hta) programme research funding and uk burden of disease
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797405/
https://www.ncbi.nlm.nih.gov/pubmed/29394905
http://dx.doi.org/10.1186/s13063-018-2489-7
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