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Evidence for widespread dysregulation of circadian clock progression in human cancer

The ubiquitous daily rhythms in mammalian physiology are guided by progression of the circadian clock. In mice, systemic disruption of the clock can promote tumor growth. In vitro, multiple oncogenes can disrupt the clock. However, due to the difficulties of studying circadian rhythms in solid tissu...

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Detalles Bibliográficos
Autores principales: Shilts, Jarrod, Chen, Guanhua, Hughey, Jacob J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797448/
https://www.ncbi.nlm.nih.gov/pubmed/29404219
http://dx.doi.org/10.7717/peerj.4327