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Evidence for widespread dysregulation of circadian clock progression in human cancer
The ubiquitous daily rhythms in mammalian physiology are guided by progression of the circadian clock. In mice, systemic disruption of the clock can promote tumor growth. In vitro, multiple oncogenes can disrupt the clock. However, due to the difficulties of studying circadian rhythms in solid tissu...
Autores principales: | Shilts, Jarrod, Chen, Guanhua, Hughey, Jacob J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PeerJ Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797448/ https://www.ncbi.nlm.nih.gov/pubmed/29404219 http://dx.doi.org/10.7717/peerj.4327 |
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