Alpha 1 antitrypsin to treat lung disease in alpha 1 antitrypsin deficiency: recent developments and clinical implications

Alpha 1 antitrypsin deficiency is a hereditary condition characterized by low alpha 1 proteinase inhibitor (also known as alpha 1 antitrypsin [AAT]) serum levels. Reduced levels of AAT allow abnormal degradation of lung tissue, which may ultimately lead to the development of early-onset emphysema. I...

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Detalles Bibliográficos
Autores principales: Chapman, Kenneth R, Chorostowska-Wynimko, Joanna, Koczulla, A Rembert, Ferrarotti, Ilaria, McElvaney, Noel G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797472/
https://www.ncbi.nlm.nih.gov/pubmed/29430176
http://dx.doi.org/10.2147/COPD.S149429

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