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TLR3 Ligand Poly(I:C) Exerts Distinct Actions in Synovial Fibroblasts When Delivered by Extracellular Vesicles

Extracellular vesicles (EV) can modulate the responses of cells to toll-like receptor (TLR) ligation; conversely, TLR ligands such as double-stranded RNA (dsRNA) can enhance the release of EV and influence of the composition and functions of EV cargos. Inflamed synovial joints in rheumatoid arthriti...

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Detalles Bibliográficos
Autores principales:	Frank-Bertoncelj, Mojca, Pisetsky, David S., Kolling, Christoph, Michel, Beat A., Gay, Renate E., Jüngel, Astrid, Gay, Steffen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797482/ https://www.ncbi.nlm.nih.gov/pubmed/29434584 http://dx.doi.org/10.3389/fimmu.2018.00028

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