Hydroponic Treatment of Nicotiana benthamiana with Kifunensine Modifies the N-glycans of Recombinant Glycoprotein Antigens to Predominantly Man9 High-Mannose Type upon Transient Overexpression

Nicotiana benthamiana transient overexpression systems offer unique advantages for rapid and scalable biopharmaceuticals production, including high scalability and eukaryotic post-translational modifications such as N-glycosylation. High-mannose-type glycans (HMGs) of glycoprotein antigens have been...

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Detalles Bibliográficos
Autores principales: Roychowdhury, Sugata, Oh, Young J., Kajiura, Hiroyuki, Hamorsky, Krystal T., Fujiyama, Kazuhito, Matoba, Nobuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Plant Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797603/
https://www.ncbi.nlm.nih.gov/pubmed/29441088
http://dx.doi.org/10.3389/fpls.2018.00062

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