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Metabolomics Based Identification of SIRT5 and Protein Kinase C Epsilon Regulated Pathways in Brain

The role of Sirtuins in brain function is emerging, yet little is known about SIRT5 in this domain. Our previous work demonstrates that protein kinase C epsilon (PKCε)-induced protection from focal ischemia is lost in SIRT5(−/−) mice. Thus, metabolic regulation by SIRT5 contributes significantly to...

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Detalles Bibliográficos
Autores principales:	Koronowski, Kevin B., Khoury, Nathalie, Morris-Blanco, Kahlilia C., Stradecki-Cohan, Holly M., Garrett, Timothy J., Perez-Pinzon, Miguel A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797631/ https://www.ncbi.nlm.nih.gov/pubmed/29440987 http://dx.doi.org/10.3389/fnins.2018.00032

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