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Whole exome sequencing to identify genetic markers for trastuzumab‐induced cardiotoxicity

Although trastuzumab‐induced cardiotoxicity is an important determinant to limit the use of this drug, the molecular mechanism of risk for this toxicity is not well understood. To identify genetic variants determining the risk of trastuzumab‐induced cardiotoxicity, we carried out whole exome sequenc...

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Detalles Bibliográficos
Autores principales:	Udagawa, Chihiro, Nakamura, Hiromi, Ohnishi, Hiroshi, Tamura, Kenji, Shimoi, Tatsunori, Yoshida, Masayuki, Yoshida, Teruhiko, Totoki, Yasushi, Shibata, Tatsuhiro, Zembutsu, Hitoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797809/ https://www.ncbi.nlm.nih.gov/pubmed/29247589 http://dx.doi.org/10.1111/cas.13471

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