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Downregulation of 15‐hydroxyprostaglandin dehydrogenase by interleukin‐1β from activated macrophages leads to poor prognosis in pancreatic cancer

Chronic inflammation has a crucial role in cancer development and the progression of various tumors, including pancreatic ductal adenocarcinoma (PDAC). The arachidonate cascade is a major inflammatory pathway that produces several metabolites, such as prostaglandin E2. The enzyme 15‐hydroxyprostagla...

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Detalles Bibliográficos
Autores principales:	Arima, Kota, Komohara, Yoshihiro, Bu, Luke, Tsukamoto, Masayo, Itoyama, Rumi, Miyake, Keisuke, Uchihara, Tomoyuki, Ogata, Yoko, Nakagawa, Shigeki, Okabe, Hirohisa, Imai, Katsunori, Hashimoto, Daisuke, Chikamoto, Akira, Yamashita, Yo‐ichi, Baba, Hideo, Ishimoto, Takatsugu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797824/ https://www.ncbi.nlm.nih.gov/pubmed/29224225 http://dx.doi.org/10.1111/cas.13467

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