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Newcastle disease virus co‐expressing interleukin 7 and interleukin 15 modified tumor cells as a vaccine for cancer immunotherapy
Interleukin 15 (IL15) and IL7 are two cytokines essential for T cell development and homeostasis. In order to improve the antitumor activity by Newcastle disease virus (NDV)‐modified tumor vaccine, we generated a recombinant NDV co‐expressing IL15 and IL7 (LX/IL(15+7)) through incorporation of a 2A...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797827/ https://www.ncbi.nlm.nih.gov/pubmed/29224228 http://dx.doi.org/10.1111/cas.13468 |