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Role of the Ca(2+)-Calcineurin-Nuclear Factor of Activated T cell Pathway in Mitofusin-2-Mediated Immune Function of Jurkat Cells

BACKGROUND: Mitofusin-2 (MFN2), a well-known mitochondrial fusion protein, has been shown to participate in innate immunity, but its role in mediating adaptive immunity remains poorly characterized. In this study, we explored the potential role of MFN2 in mediating the immune function of T lymphocyt...

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Detalles Bibliográficos
Autores principales: Xu, Xiu-Ping, Yao, Yong-Ming, Zhao, Guang-Ju, Wu, Zong-Sheng, Li, Jun-Cong, Jiang, Yun-Long, Lu, Zhong-Qiu, Hong, Guang-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798055/
https://www.ncbi.nlm.nih.gov/pubmed/29363649
http://dx.doi.org/10.4103/0366-6999.223855