Significance of (18)F-sodium Fluoride Positron Emission Tomography in Characterization of POEMS Osteosclerotic Lesions Better Than (18)F-fluorodeoxyglucose Positron Emission Tomography

Crow-Fukase syndrome (POEMS syndrome) is a rare systemic paraneoplastic syndrome. Bone lesions are manifested by sclerotic osteoblastic lesions often associated with bone pain. Characterization of osseous lesions is always crucial for clinical correlation and better patient management. We present a...

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Detalles Bibliográficos
Autores principales: Marafi, Fahad Abdul Rehman, Rasheed, Rashid, Usmani, Sharjeel, Alkandari, Fareeda, Iqbal, Anam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798109/
https://www.ncbi.nlm.nih.gov/pubmed/29430125
http://dx.doi.org/10.4103/ijnm.IJNM_125_17
Descripción
Sumario:Crow-Fukase syndrome (POEMS syndrome) is a rare systemic paraneoplastic syndrome. Bone lesions are manifested by sclerotic osteoblastic lesions often associated with bone pain. Characterization of osseous lesions is always crucial for clinical correlation and better patient management. We present a case where (18)F-fluorodeoxyglucose positron emission tomography ((18)F-FDG PET/CT) was unable to characterize a clinically symptomatic patient, and (18)F-fluoride PET/CT showed excellent characterization of osteosclerotic lesions. The results were in correlation with already published data and showed that (18)F-fluoride PET/CT has better uptake in osteoblastic lesions in POEMS syndrome when compared to (18)F-FDG PET/CT and have superior imaging quality in assessing the bone lesions.

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