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Depressive affect in incident hemodialysis patients
BACKGROUND: The prevalence of depressive affect is not well defined in the incident hemodialysis (HD) population. We investigated the prevalence of and associated risk factors and hospitalization rates for depressive affect in incident HD patients. METHODS: We performed a prospective investigation u...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798120/ https://www.ncbi.nlm.nih.gov/pubmed/29423211 http://dx.doi.org/10.1093/ckj/sfx054 |
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author | McDougall, Kathryn A Larkin, John W Wingard, Rebecca L Jiao, Yue Rosen, Sophia Ma, Lin Usvyat, Len A Maddux, Franklin W |
author_facet | McDougall, Kathryn A Larkin, John W Wingard, Rebecca L Jiao, Yue Rosen, Sophia Ma, Lin Usvyat, Len A Maddux, Franklin W |
author_sort | McDougall, Kathryn A |
collection | PubMed |
description | BACKGROUND: The prevalence of depressive affect is not well defined in the incident hemodialysis (HD) population. We investigated the prevalence of and associated risk factors and hospitalization rates for depressive affect in incident HD patients. METHODS: We performed a prospective investigation using the Patient Health Questionnaire 2 (PHQ2) depressive affect assessment. From January to July of 2013 at 108 in-center clinics randomly selected across tertiles of baseline quality measures, we contacted 577 and 543 patients by telephone for depressive affect screening. PHQ2 test scores range from 0 to 6 (scores ≥3 suggest the presence of depressive affect). The prevalence of depressive affect was measured at 1–30 and 121–150 days after initiating HD; depressive affect risk factors and hospitalization rates by depressive affect status at 1–30 days after starting HD were computed. RESULTS: Of 1120 contacted patients, 340 completed the PHQ2. In patients screened at 1–30 or 121–150 days after starting HD, depressive affect prevalence was 20.2% and 18.5%, respectively (unpaired t-test, P = 0.7). In 35 patients screened at both time points, there were trends for lower prevalence of depressive affect at the end of incident HD, with 20.0% and 5.7% of patients positive for depressive affect at 1–30 and 121–150 days, respectively (paired t-test, P = 0.1). Hospitalization rates were higher in patients with depressive affect during the first 30 days, exhibiting 1.5 more admissions (P < 0.001) and 10.5 additional hospital days (P = 0.008) per patient-year. Females were at higher risk for depressive affect at 1–30 days (P = 0.01). CONCLUSIONS: The prevalence of depressive affect in HD patients is high throughout the incident period. Rates of hospital admissions and hospital days are increased in incident HD patients with depressive affect. |
format | Online Article Text |
id | pubmed-5798120 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-57981202018-02-08 Depressive affect in incident hemodialysis patients McDougall, Kathryn A Larkin, John W Wingard, Rebecca L Jiao, Yue Rosen, Sophia Ma, Lin Usvyat, Len A Maddux, Franklin W Clin Kidney J Renal Replacement Therapy BACKGROUND: The prevalence of depressive affect is not well defined in the incident hemodialysis (HD) population. We investigated the prevalence of and associated risk factors and hospitalization rates for depressive affect in incident HD patients. METHODS: We performed a prospective investigation using the Patient Health Questionnaire 2 (PHQ2) depressive affect assessment. From January to July of 2013 at 108 in-center clinics randomly selected across tertiles of baseline quality measures, we contacted 577 and 543 patients by telephone for depressive affect screening. PHQ2 test scores range from 0 to 6 (scores ≥3 suggest the presence of depressive affect). The prevalence of depressive affect was measured at 1–30 and 121–150 days after initiating HD; depressive affect risk factors and hospitalization rates by depressive affect status at 1–30 days after starting HD were computed. RESULTS: Of 1120 contacted patients, 340 completed the PHQ2. In patients screened at 1–30 or 121–150 days after starting HD, depressive affect prevalence was 20.2% and 18.5%, respectively (unpaired t-test, P = 0.7). In 35 patients screened at both time points, there were trends for lower prevalence of depressive affect at the end of incident HD, with 20.0% and 5.7% of patients positive for depressive affect at 1–30 and 121–150 days, respectively (paired t-test, P = 0.1). Hospitalization rates were higher in patients with depressive affect during the first 30 days, exhibiting 1.5 more admissions (P < 0.001) and 10.5 additional hospital days (P = 0.008) per patient-year. Females were at higher risk for depressive affect at 1–30 days (P = 0.01). CONCLUSIONS: The prevalence of depressive affect in HD patients is high throughout the incident period. Rates of hospital admissions and hospital days are increased in incident HD patients with depressive affect. Oxford University Press 2018-02 2017-07-11 /pmc/articles/PMC5798120/ /pubmed/29423211 http://dx.doi.org/10.1093/ckj/sfx054 Text en © The Author 2017. Published by Oxford University Press on behalf of ERA-EDTA. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Renal Replacement Therapy McDougall, Kathryn A Larkin, John W Wingard, Rebecca L Jiao, Yue Rosen, Sophia Ma, Lin Usvyat, Len A Maddux, Franklin W Depressive affect in incident hemodialysis patients |
title | Depressive affect in incident hemodialysis patients |
title_full | Depressive affect in incident hemodialysis patients |
title_fullStr | Depressive affect in incident hemodialysis patients |
title_full_unstemmed | Depressive affect in incident hemodialysis patients |
title_short | Depressive affect in incident hemodialysis patients |
title_sort | depressive affect in incident hemodialysis patients |
topic | Renal Replacement Therapy |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798120/ https://www.ncbi.nlm.nih.gov/pubmed/29423211 http://dx.doi.org/10.1093/ckj/sfx054 |
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