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Seroepidemiology of Toxoplasma gondii Infection in Women of Reproductive Age: A Cross-Sectional Study in a Northwestern Mexican City

BACKGROUND: Through a cross-sectional survey, we determined the seroprevalence and correlates of Toxoplasma gondii (T. gondii) infection in women of reproductive age in Hermosillo City, Mexico. METHODS: We studied 445 women of reproductive age in Hermosillo City in the northwestern Mexican state of...

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Autores principales: Alvarado-Esquivel, Cosme, Corella-Madueno, Maria Alba Guadalupe, Hernandez-Tinoco, Jesus, Rascon-Careaga, Antonio, Sanchez-Anguiano, Luis Francisco, Martinez-Robinson, Karla Guadalupe, Aldana-Madrid, Maria Lourdes, Quizan-Plata, Trinidad, Canez-Carrasco, Maria Guadalupe, Perez-Martinez, Cinthia Jhovanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elmer Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798267/
https://www.ncbi.nlm.nih.gov/pubmed/29416579
http://dx.doi.org/10.14740/jocmr3284w
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author Alvarado-Esquivel, Cosme
Corella-Madueno, Maria Alba Guadalupe
Hernandez-Tinoco, Jesus
Rascon-Careaga, Antonio
Sanchez-Anguiano, Luis Francisco
Martinez-Robinson, Karla Guadalupe
Aldana-Madrid, Maria Lourdes
Quizan-Plata, Trinidad
Canez-Carrasco, Maria Guadalupe
Perez-Martinez, Cinthia Jhovanna
author_facet Alvarado-Esquivel, Cosme
Corella-Madueno, Maria Alba Guadalupe
Hernandez-Tinoco, Jesus
Rascon-Careaga, Antonio
Sanchez-Anguiano, Luis Francisco
Martinez-Robinson, Karla Guadalupe
Aldana-Madrid, Maria Lourdes
Quizan-Plata, Trinidad
Canez-Carrasco, Maria Guadalupe
Perez-Martinez, Cinthia Jhovanna
author_sort Alvarado-Esquivel, Cosme
collection PubMed
description BACKGROUND: Through a cross-sectional survey, we determined the seroprevalence and correlates of Toxoplasma gondii (T. gondii) infection in women of reproductive age in Hermosillo City, Mexico. METHODS: We studied 445 women of reproductive age in Hermosillo City in the northwestern Mexican state of Sonora. Women were enrolled in the University of Sonora. Sera of women were examined for IgG and IgM antibodies to T. gondii by commercially available enzyme immunoassays. The association of T. gondii seropositivity with the characteristics of the pregnant women was determined by bivariate and multivariate analyses. RESULTS: Of the 445 women (mean age: 22.18 ± 5.6 years) studied, 16 (3.6%) had IgG antibodies to T. gondii, and two (12.5%) were also positive for IgM antibodies to T. gondii. Of the 16 anti-T. gondii IgG-positive women, six (37.5%) had IgG levels higher than 150 IU/mL, four (25.0%) between 100 and 150 IU/mL, and six (37.5%) between 9 and 99 IU/mL. Multivariate analysis of socio-demographic and behavioral variables showed that T. gondii seropositivity was associated with older age (odds ratio (OR): 5.30; 95% confidence interval (CI): 1.37 - 20.50; P = 0.01) and boar meat consumption (OR: 6.86; 95% CI: 1.27 - 37.07; P = 0.02). CONCLUSIONS: Women of reproductive age in Hermosillo City had a low seroprevalence of T. gondii infection. However, this finding indicates that most of these women were susceptible to a primary infection. Factors associated with T. gondii infection found in this study may be useful for the optimal planning of preventive measures against T. gondii infection and its sequelae.
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spelling pubmed-57982672018-02-07 Seroepidemiology of Toxoplasma gondii Infection in Women of Reproductive Age: A Cross-Sectional Study in a Northwestern Mexican City Alvarado-Esquivel, Cosme Corella-Madueno, Maria Alba Guadalupe Hernandez-Tinoco, Jesus Rascon-Careaga, Antonio Sanchez-Anguiano, Luis Francisco Martinez-Robinson, Karla Guadalupe Aldana-Madrid, Maria Lourdes Quizan-Plata, Trinidad Canez-Carrasco, Maria Guadalupe Perez-Martinez, Cinthia Jhovanna J Clin Med Res Original Article BACKGROUND: Through a cross-sectional survey, we determined the seroprevalence and correlates of Toxoplasma gondii (T. gondii) infection in women of reproductive age in Hermosillo City, Mexico. METHODS: We studied 445 women of reproductive age in Hermosillo City in the northwestern Mexican state of Sonora. Women were enrolled in the University of Sonora. Sera of women were examined for IgG and IgM antibodies to T. gondii by commercially available enzyme immunoassays. The association of T. gondii seropositivity with the characteristics of the pregnant women was determined by bivariate and multivariate analyses. RESULTS: Of the 445 women (mean age: 22.18 ± 5.6 years) studied, 16 (3.6%) had IgG antibodies to T. gondii, and two (12.5%) were also positive for IgM antibodies to T. gondii. Of the 16 anti-T. gondii IgG-positive women, six (37.5%) had IgG levels higher than 150 IU/mL, four (25.0%) between 100 and 150 IU/mL, and six (37.5%) between 9 and 99 IU/mL. Multivariate analysis of socio-demographic and behavioral variables showed that T. gondii seropositivity was associated with older age (odds ratio (OR): 5.30; 95% confidence interval (CI): 1.37 - 20.50; P = 0.01) and boar meat consumption (OR: 6.86; 95% CI: 1.27 - 37.07; P = 0.02). CONCLUSIONS: Women of reproductive age in Hermosillo City had a low seroprevalence of T. gondii infection. However, this finding indicates that most of these women were susceptible to a primary infection. Factors associated with T. gondii infection found in this study may be useful for the optimal planning of preventive measures against T. gondii infection and its sequelae. Elmer Press 2018-03 2018-01-26 /pmc/articles/PMC5798267/ /pubmed/29416579 http://dx.doi.org/10.14740/jocmr3284w Text en Copyright 2018, Alvarado-Esquivel et al. http://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution Non-Commercial 4.0 International License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Alvarado-Esquivel, Cosme
Corella-Madueno, Maria Alba Guadalupe
Hernandez-Tinoco, Jesus
Rascon-Careaga, Antonio
Sanchez-Anguiano, Luis Francisco
Martinez-Robinson, Karla Guadalupe
Aldana-Madrid, Maria Lourdes
Quizan-Plata, Trinidad
Canez-Carrasco, Maria Guadalupe
Perez-Martinez, Cinthia Jhovanna
Seroepidemiology of Toxoplasma gondii Infection in Women of Reproductive Age: A Cross-Sectional Study in a Northwestern Mexican City
title Seroepidemiology of Toxoplasma gondii Infection in Women of Reproductive Age: A Cross-Sectional Study in a Northwestern Mexican City
title_full Seroepidemiology of Toxoplasma gondii Infection in Women of Reproductive Age: A Cross-Sectional Study in a Northwestern Mexican City
title_fullStr Seroepidemiology of Toxoplasma gondii Infection in Women of Reproductive Age: A Cross-Sectional Study in a Northwestern Mexican City
title_full_unstemmed Seroepidemiology of Toxoplasma gondii Infection in Women of Reproductive Age: A Cross-Sectional Study in a Northwestern Mexican City
title_short Seroepidemiology of Toxoplasma gondii Infection in Women of Reproductive Age: A Cross-Sectional Study in a Northwestern Mexican City
title_sort seroepidemiology of toxoplasma gondii infection in women of reproductive age: a cross-sectional study in a northwestern mexican city
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798267/
https://www.ncbi.nlm.nih.gov/pubmed/29416579
http://dx.doi.org/10.14740/jocmr3284w
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