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Naked mole-rat acid-sensing ion channel 3 forms nonfunctional homomers, but functional heteromers
Acid-sensing ion channels (ASICs) form both homotrimeric and heterotrimeric ion channels that are activated by extracellular protons and are involved in a wide range of physiological and pathophysiological processes, including pain and anxiety. ASIC proteins can form both homotrimeric and heterotrim...
Autores principales: | Schuhmacher, Laura-Nadine, Callejo, Gerard, Srivats, Shyam, Smith, Ewan St. John |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798305/ https://www.ncbi.nlm.nih.gov/pubmed/29237731 http://dx.doi.org/10.1074/jbc.M117.807859 |
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