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Infected erythrocytes expressing DC13 PfEMP1 differ from recombinant proteins in EPCR-binding function

Recent advances have identified a new paradigm for cerebral malaria pathogenesis in which endothelial protein C receptor (EPCR) is a major host receptor for sequestration of Plasmodium falciparum-infected erythrocytes (IEs) in the brain and other vital organs. The parasite adhesins that bind EPCR ar...

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Detalles Bibliográficos
Autores principales:	Azasi, Yvonne, Lindergard, Gabriella, Ghumra, Ashfaq, Mu, Jianbing, Miller, Louis H., Rowe, J. Alexandra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2018
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798336/ https://www.ncbi.nlm.nih.gov/pubmed/29339517 http://dx.doi.org/10.1073/pnas.1712879115

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