Enhancer adoption caused by genomic insertion elicits interdigital Shh expression and syndactyly in mouse

Acquisition of new cis-regulatory elements (CREs) can cause alteration of developmental gene regulation and may introduce morphological novelty in evolution. Although structural variation in the genome generated by chromosomal rearrangement is one possible source of new CREs, only a few examples are...

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Detalles Bibliográficos
Autores principales: Mouri, Kousuke, Sagai, Tomoko, Maeno, Akiteru, Amano, Takanori, Toyoda, Atsushi, Shiroishi, Toshihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798340/
https://www.ncbi.nlm.nih.gov/pubmed/29255029
http://dx.doi.org/10.1073/pnas.1713339115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798340/
https://www.ncbi.nlm.nih.gov/pubmed/29255029
http://dx.doi.org/10.1073/pnas.1713339115

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