Role of intestinal flora in colorectal cancer from the metabolite perspective: a systematic review

Colorectal cancer is one of the most common human malignant tumors. Recent research has shown that colorectal cancer is a dysbacteriosis-induced disease; however, the role of intestinal bacteria in colorectal cancer is unclear. This review explores the role of intestinal flora in colorectal cancer....

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Autores principales: Han, Shuwen, Gao, Jianlan, Zhou, Qing, Liu, Shanshan, Wen, Caixia, Yang, Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798565/
https://www.ncbi.nlm.nih.gov/pubmed/29440929
http://dx.doi.org/10.2147/CMAR.S153482
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author Han, Shuwen
Gao, Jianlan
Zhou, Qing
Liu, Shanshan
Wen, Caixia
Yang, Xi
author_facet Han, Shuwen
Gao, Jianlan
Zhou, Qing
Liu, Shanshan
Wen, Caixia
Yang, Xi
author_sort Han, Shuwen
collection PubMed
description Colorectal cancer is one of the most common human malignant tumors. Recent research has shown that colorectal cancer is a dysbacteriosis-induced disease; however, the role of intestinal bacteria in colorectal cancer is unclear. This review explores the role of intestinal flora in colorectal cancer. In total, 57 articles were included after identification and screening. The pertinent literature on floral metabolites in colorectal cancer from three metabolic perspectives – including carbohydrate, lipid, and amino acid metabolism – was analyzed. An association network regarding the role of intestinal flora from a metabolic perspective was constructed by analyzing the previous literature to provide direction and insight for further research on intestinal flora in colorectal cancer.
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spelling pubmed-57985652018-02-13 Role of intestinal flora in colorectal cancer from the metabolite perspective: a systematic review Han, Shuwen Gao, Jianlan Zhou, Qing Liu, Shanshan Wen, Caixia Yang, Xi Cancer Manag Res Review Colorectal cancer is one of the most common human malignant tumors. Recent research has shown that colorectal cancer is a dysbacteriosis-induced disease; however, the role of intestinal bacteria in colorectal cancer is unclear. This review explores the role of intestinal flora in colorectal cancer. In total, 57 articles were included after identification and screening. The pertinent literature on floral metabolites in colorectal cancer from three metabolic perspectives – including carbohydrate, lipid, and amino acid metabolism – was analyzed. An association network regarding the role of intestinal flora from a metabolic perspective was constructed by analyzing the previous literature to provide direction and insight for further research on intestinal flora in colorectal cancer. Dove Medical Press 2018-01-31 /pmc/articles/PMC5798565/ /pubmed/29440929 http://dx.doi.org/10.2147/CMAR.S153482 Text en © 2018 Han et al. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Review
Han, Shuwen
Gao, Jianlan
Zhou, Qing
Liu, Shanshan
Wen, Caixia
Yang, Xi
Role of intestinal flora in colorectal cancer from the metabolite perspective: a systematic review
title Role of intestinal flora in colorectal cancer from the metabolite perspective: a systematic review
title_full Role of intestinal flora in colorectal cancer from the metabolite perspective: a systematic review
title_fullStr Role of intestinal flora in colorectal cancer from the metabolite perspective: a systematic review
title_full_unstemmed Role of intestinal flora in colorectal cancer from the metabolite perspective: a systematic review
title_short Role of intestinal flora in colorectal cancer from the metabolite perspective: a systematic review
title_sort role of intestinal flora in colorectal cancer from the metabolite perspective: a systematic review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798565/
https://www.ncbi.nlm.nih.gov/pubmed/29440929
http://dx.doi.org/10.2147/CMAR.S153482
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