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A novel therapeutic strategy for cartilage diseases based on lipid nanoparticle-RNAi delivery system

BACKGROUND: Cartilage degeneration affects millions of people but preventing its degeneration is a big challenge. Although RNA interference (RNAi) has been used in human trials via silencing specific genes, the cartilage RNAi has not been possible to date because the cartilage is an avascular and ve...

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Detalles Bibliográficos
Autores principales:	Wang, Shaowei, Wei, Xiaochun, Sun, Xiaojuan, Chen, Chongwei, Zhou, Jingming, Zhang, Ge, Wu, Heng, Guo, Baosheng, Wei, Lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798567/ https://www.ncbi.nlm.nih.gov/pubmed/29440889 http://dx.doi.org/10.2147/IJN.S142797

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