MicroRNAs in CSF as prodromal biomarkers for Huntington disease in the PREDICT-HD study

OBJECTIVE: To investigate the feasibility of microRNA (miRNA) levels in CSF as biomarkers for prodromal Huntington disease (HD). METHODS: miRNA levels were measured in CSF from 60 PREDICT-HD study participants using the HTG protocol. Using a CAG–Age Product score, 30 prodromal HD participants were s...

Descripción completa

Detalles Bibliográficos
Autores principales: Reed, Eric R., Latourelle, Jeanne C., Bockholt, Jeremy H., Bregu, Joli, Smock, Justin, Paulsen, Jane S., Myers, Richard H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798654/
https://www.ncbi.nlm.nih.gov/pubmed/29282329
http://dx.doi.org/10.1212/WNL.0000000000004844

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798654/
https://www.ncbi.nlm.nih.gov/pubmed/29282329
http://dx.doi.org/10.1212/WNL.0000000000004844

Ejemplares similares