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RLE plots: Visualizing unwanted variation in high dimensional data

Unwanted variation can be highly problematic and so its detection is often crucial. Relative log expression (RLE) plots are a powerful tool for visualizing such variation in high dimensional data. We provide a detailed examination of these plots, with the aid of examples and simulation, explaining w...

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Detalles Bibliográficos
Autores principales: Gandolfo, Luke C., Speed, Terence P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798764/
https://www.ncbi.nlm.nih.gov/pubmed/29401521
http://dx.doi.org/10.1371/journal.pone.0191629