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Attenuation of reactive gliosis in stroke-injured mouse brain does not affect neurogenesis from grafted human iPSC-derived neural progenitors
Induced pluripotent stem cells (iPSCs) or their progeny, derived from human somatic cells, can give rise to functional improvements after intracerebral transplantation in animal models of stroke. Previous studies have indicated that reactive gliosis, which is associated with stroke, inhibits neuroge...
Autores principales: | Laterza, Cecilia, Uoshima, Naomi, Tornero, Daniel, Wilhelmsson, Ulrika, Stokowska, Anna, Ge, Ruimin, Pekny, Milos, Lindvall, Olle, Kokaia, Zaal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798785/ https://www.ncbi.nlm.nih.gov/pubmed/29401502 http://dx.doi.org/10.1371/journal.pone.0192118 |
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