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Attenuation of reactive gliosis in stroke-injured mouse brain does not affect neurogenesis from grafted human iPSC-derived neural progenitors

Induced pluripotent stem cells (iPSCs) or their progeny, derived from human somatic cells, can give rise to functional improvements after intracerebral transplantation in animal models of stroke. Previous studies have indicated that reactive gliosis, which is associated with stroke, inhibits neuroge...

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Detalles Bibliográficos
Autores principales: Laterza, Cecilia, Uoshima, Naomi, Tornero, Daniel, Wilhelmsson, Ulrika, Stokowska, Anna, Ge, Ruimin, Pekny, Milos, Lindvall, Olle, Kokaia, Zaal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798785/
https://www.ncbi.nlm.nih.gov/pubmed/29401502
http://dx.doi.org/10.1371/journal.pone.0192118

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